Turkey 2010 Progarm

Conference Program

 International Cell Death Society Symposium


Multidisciplinary Approaches in Cell Death Research

From Yeast to Man

Limak Limra Hotel, Kemer-Antalya, Turkey

May 28-31, 2010

 [Date of last update: May 09, 2010]


Devrim Gözüaçik, Richard A. Lockshin, Melek Öztürk; Zahra Zakeri

Organizing Committee

Ray Birge, Devrim Gözüaçik, Richard A. Lockshin, Roya Khosravi-Far,Melek Öztürk; Nader Maghsoudi; Zahra Zakeri


Tentative Meeting Program

Friday May 28th 2010


  1. 9:00AM - 7:00PM


Welcome, Introduction, and Awards: 


Chair: Zahra Zakeri, Queens College of C.U.N.Y, U.S.A


4:00 - 4:15pm           Introduction and welcome

                                    Zahra Zakeri: Queens College of C.U.N.Y., U.S.A.

Cell death and different model systems

Chair: Katharina D’Herde; Univ. Ghent, Belgium


4:15 - 4:45pm           Programmed Cell Death in Yeast: Subroutines, Mechanisms and Purposes

                                    Frank Madeo:  Univ. Graz, Austria


4:45 - 5:15pm          Control of cell death by bacterial infection

Thomas Rudel: Lehrstuhl für Mikrobiologie Würzburg 


5:15 - 5:30pm           Hsp27 serine-specific phosphorylation is required for the suppression of ask1 activity and neuroprotective effect against ischemic neuronal injury

             R Anne Stetler, Univ.of Pittsburgh, USA

5:30 - 6:45pm           Calcium-sensing receptor-mediated survival in granulosa cells
AraceliDiez-FraileGhent University, Ghent, Belgium

6:45 - 6:15pm          Necrotic cell death and the protective role of the heat shock response

Nektarios Tavernarakis: Inst. Molec. Biol. Biotechnol., Greece

7:30pm                      Social hour, and Dinner

Saturday 29 May  2010

Chair: Nader Maghsoudi: Shahid Beheshti Univ. Iran 

9:00 - 9:30am           Huntington's disease: linking huntingtin function in cellular dynamics to the control of neuronal death

                                    Frederic Saudou: Institut Curie, France


9:30 - 10:00am         Developmental control of apoptosis and proliferation by the Hippo pathway

Nic Tapon: London Research Institute UK

10:00 - 10:30am       Redox regulated Cell Survival Strategies

Tom Cotter: Univ. College Cork, Ireland

10:30 – 11:00am      Coffee Break          

New approaches in studying the dynamics of cell death and manipulating them:


Chair: Simone Fulda: Uniklinik Ulm, Germany


11:00-11:30am        Linking between human apoptosis and genome stability gene networks: an example for whole genome evolution

Rita M. C. de Almeida: Univ. Fed. Rio Grande do Sul, Brazil

11:3 0- 12:00am      Studying the complexity of cell death by combining reductionist with systems level approaches

Adi Kimchi: Weizmann Inst., Israel

12:00 - 12:30pm      Rancid smell of death: oxidative lipidomics of apoptosis
Valerian E. Kagan, University of Pittsburgh, USA

12:30 - 1:00pm         Identification of proteolytic events in the membrane fraction of apoptotic cells using a quantitative proteomics approach

Huseyin Mehmet: Merck, U.S. A


1:00 - 2:00pm           Lunch           


Regulation of cell death in cancer


Chair: Soraya Smaili, Univ São Paolo, Brazil


2:00 - 2:30pm          Sensitization of small cell lung carcinoma cells to TRAIL-induced apoptosis

Boris Zhivotovsky: Karolinska Institutet, Sweden


2:30 - 3:00pm          Evaluation of Apoptotic-Inducing Properties of Indigenous Medicinal Plants in Cancer Cells

                                    Marianne J Cronje: Univ. Johannesburg, South Africa


3:00 - 3:30pm          Ubiquitin-mediated regulation of apoptosis

                                    Pascal Meier: Institute of Cancer Research, UK

3:30 - 4:00pm           Coffee


Chair: Melek Öztürk: Istanbul Univ. Turkey 


4:00 - 4:30pm           Caspase-9 promoter polymorphisms and ovary cancer

                                    Melek Öztürk: Istanbul Univ. Turkey


4:30 - 5:00pm           Regulation of autophagy in mammals: the role of Ambra1

                                    Mauro Piacentini: Univ. Di Roma Tor Vergata & Hop. Spallanzani, Italy

5:00 - 5:30pm           Apoptotic properties of EGCG, a major component of green tea, in HCT-116 human colon cancer cells

                                    Semra Koçtürk: Dokuz Eylül Üniv., Turkey


5:30 - 7:30pm           Posters


7:30-                           Dinner



Sunday, May 30st  2010


Regulation of  cell death

Chair: Selma Yilmazer Istanbul Univ. Turkey


9:00 - 9:30am           Keeping mitochondria in shape: A matter of life and death

                                    Luca Scorrano: Univ. Geneva, Switzerland


9:30 - 10:00am         Apoptosis: From the beginning to the end of life

                                    Seda Vatansever: Celal Bayar University, Turkey 


10:00 - 10:30am       Lysosomes as mediators or amplifiers of cell death?

                                    Boris Turk: Stefan Institute, Slovenia


10:30 - 11:00am       Coffee


Regulation of  cell death:


Chair: Ray Birge, UMDNJ, USA


11:00 - 11:30am       Apoptotic Cell Death and Tolerance

                                    Peter Krammer: Univ. Heidelberg, Germany


11:30 -12:00noon   Lysosomal Sphingolipid Metabolism as a Target for Cancer Therapy

                                    Marja Jäättelä: Danish Cancer Society, Denmark


12:00 - 12:30pm      Cellular senescence and immortality in liver cancer

Mehmet Ozturk: Institut Albert Bonniot Grenoble, France

12:30 - 12:45pm      Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-dependent ERK and JNK activation
Shazib Pervaiz Graduate Medical School, Singapore


12:45 - 1:00pm         New role for an anti-atherosclerotic enzyme: pon2 confers apoptosis resistance and is overexpressed in tumors

Sven Horke, Univ. of Medicine, Mainz, Germany

1:00 - 2:00pm           Lunch


Regulation of  cell death:


Chair: Marie Lise Gougeon: Institut Pasteur, France


2:00 - 2:30pm           With or without AIF

                                    Nazanine Modjtahedi: INSERM, Institut Gustave-Roussy, France   

2:30 - 3:00pm           Caspase-14 is required for epidermal cornification 

Wim Declercq: Faculty of Medicine, Leuven, Belgium


3:00 - 3:15pm           Doxorubicin and tamoxifen induce autophagy as a survival pathway through calmodulin-dependent protein kinase III (CAMK-III) in primary ER(-) and ER(+), drug resistant and metastatic breast cancer cells

                                    Bulent Ozpolat, Eskisehir Osmangazi University, Medical Faculty, Eskisehir, Turkey

3:15 - 3:30pm           Mcl-1 degradation by pro-inflammatory cytokines and palmitate is an early and major event for beta cell apoptosis.

Florent Allagnat, Laboratoire de Médecine Expérimentale, Université Libre de Bruxelles, Brussels, Belgium

3:30 - 4:00pm           Coffee


Workshop:               How the women in the field can survive, network and excel.


4:00 - 4:15pm           Zahra Zakeri, Queens College & Grad Center of CUNY, USA:

                                    Welcome and introductory remarks


4:15 - 4: 30pm          What is holding back female scientists?"
Anna Ledin: The Royal Swedish Academy of Sciences Stockholm, Sweden

4:30 - 6:00pm           Moderator:   Zahra Zakeri

                                    Open forum and panel discussion: Panelists:  Anna Ledin; Marianne Cronje; Marie-Lise Gougeon; Marja Jäättelä; Simone Fulda; Melek Öztürk: Patrizia Agostinis

6:00 - 8:00pm           Posters --- (Concurrent Workshop on regional collaboration)


8.00-                           Dinner



Monday 31 May 2010


Signalling in cell death:


Chair: Richard Lockshin, St. John’s University, New York, USA


9:00 - 9:15am           Presenting Award to Dr Eileen White:

Richard A. Lockshin: St. John’s University, U.S.A                                           

9:30 - 10:00am         Oncogene Activation Causes Autophagy Addiction


                                    Eileen White: Rutgers Univ. & Cancer Inst. of New Jersey, U.S.A


10:00 - 10:30am      New regulators of mammalian autophagy: Implications for cell survival and death.

Devrim Gözüaçik: Sabanci Univ. Turkey

10:30 - 11:00am       Coffee

Chair: Devrim Gözüaçik: Sabanci Univ. Turkey 

11:00 - 11:30am       ASC Activity in Melanoma

Nesrin Özören: Bo­ğaziçi UniversityTurkey

11:30 – 11:45am      A novel link between autophagy and apoptosis mediated by caspase cleavage of Atg
Ozlem Oral Biological Sciences & Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey

11:45 - 12:00am      Identification of a novel putative regulator of the major apoptotic nuclease dff.
Piotr Widlak P MSC Cancer Center and Institute of Oncology, Gliwice, Poland


12:00 - 12:30pm      Regulation of cardiac death and autophagy by local growth factors and hormones

Sergio Lavandero: Univ. de Chile, Chile


12:30 - 1:00pm         Molecular mechanisms of necrotic cell death

Peter Vandenabeele: Univ. Ghent, Belgium


1:00 - 2:00pm           Closing Remarks and End of Meeting-            Zahra Zakeri