Conference Program
The Seventh International Cell Death
Society Symposium on
Targeting cell death pathways for human diseases
Shanghai Mega City, China
June 6-9, 2008
11:00-12:00pm Meeting on establishing ICDS China chapter
Session 1: Introduction and Keynote Speaker
Chair: Zahra Zakeri: Queens College, U.S.A
2:00-2:15pm Introduction and Welcome
Zahra Zakeri: Queens College, U.S.A
2:15-2:30pm Welcome
Jiarui Wu: Shanghai Institutes for Biological Sciences, China
2:30-3:00pm Presentation of Award to Dr. H. Robert Horvitz
Richard Lockshin: St. Johns University, U.S.A
3:00-4:00pm Genetic Control of Programmed Cell Death in C. elegans
H. Robert Horvitz: MIT, U.S.A
4:00-4:30pm COFFEE
Session 2: Research and Development in China
Chair: Jiarui Wu: Shanghai Institutes for Biological Sciences, China
4:30-5:00pm R & D in China - New adventure for Astrazeneca
Xiaolin Zhang: AstraZeneca Globla R&D, China
5:00-5:30pm TRPC channels and neuronal survival
En Li: Novartis, Shanghai, China
5:30-6:00pm A New Model in Discovery of Innovative Medicine: a Look at Roche R&D Center China
Li Chen: Roche R&D center, China
7:00pm DINNER, Awards
Saturday 7th June 2008
Session 3: Pathways: Apoptosis, Necrosis, Autophagy and more
Chairs: Roya Khosravi-Far: Harvard Medical School, U.S.A
9:00-9:30am Molecular connections between different cell death pathways
Xiaodong Wang: Southwestern Medical Center, U.S.A
9:30-10:00am System level analysis of programmed cell death: switching between different death modalities
Adi Kimchi: Weizmann Insitute of Science, Israel
10:00-10:15am Pretaporter, A Drosophila Endoplasmic Reticulum Protein Serving As A Ligand For Draper In Phagocytosis Of Apoptotic Cells
Takayuki Kuraishi: Kanazawa University, Japan
10:15-10:30am Imaging Of Caspase Activation During Drosophila Development
Erina Kuranaga: University of Tokyo, Japan
10:30-11:00am COFFEE
Chair: Dengxi Zheng: Chinese Academy of Medical Science, Beijing
11:00-11:30am Regulation of autophagy
Patrice Codogno: INSERM U756, France
11:30-12:00pm Regulation of autophagy in mammals by Ambra-1 and its partners
Mauro Piacentini: University of Rome, “Tor Vergata”, Italy
12:00-12:30pm NF-kB as a regulator of apoptosis of human leukemia
Marc Diederich: Hopital Kirchberg, Luxembourg
12:30pm-2:00pm Lunch
Session 4: Signaling in Cell Death
Chair: Simone Fulda: Ulm University, Germany
2:00-2:30pm Molecular mechanisms of cytotoxic lymphocyte mediated cell death
Nigel Waterhouse: Peter MacCallum Cancer Centre, Australia
2:30-3:00pm Death pathways mediated by the granules of NK/CTLs
Zusen Fan: Institute of Biophysics, CAS, China
3:00-3:15pm Cloning and expression Of Bir3 Domain Of mouse Naip1 protein
Jamshid Davoodi: University of Tehran, Iran
3:15-3:30pm Erucylphosphohomocholine-Induced Apoptosis In Human Glioma Cells: Role Of The Oligomycin-Sensitive F0 Part Of Mitochondrial H+-Atp-Synthase
Wilfried Kugler: Universitats-Kinderklinik, Germany
3:30-4:00pm COFFEE
Chair: Marianne Cronje: University of Johannesburg, South Africa
4:00-4:30pm Death in the Oocyte
Sally A. Kornbluth: Duke University Medical Center, U.S.A
4:30-5:00pm Diversity of the roles of caspase activation during development
Masayuki Miura, University of Tokyo, Japan
5:00pm-7:00pm Poster Session
7:00pm DINNER
Sunday 8th June 2008
Session 5: Regulation of Cell Death I
Chair: Marie-Lise Gougeon: Institut Pasteur, France
9:00-9:30am Regulation of DNA-damage-induced apoptosis by protein arginine methylation in C. elegans
Chong-Lin Yang: Institute of Genetics and development, CAS, China
9:30-10:00am Molecular regulation of mitochondrial dynamics
Quan Chen: Inst. Of Zoology, Chinese Academy of Sciences, China
10:00-10:15am Cellular Pro-Apoptotic Bax and Bak Play Opposing Roles During Influenza A-Induced Cell Death
Jeff Mclean: Queens College, U.S.A
10:15-10:30am Oxidative Stress And Chaperone-Mediated Cancer Cell Death
Pedro Calderon: Université Catholique de Louvain, Belgium
10:30-11:00am COFFEE
Session 6: Regulation of Cell Death II
Chair: Nader Maghsoudi: Shaheed Behesti Medical University, Iran
11:00-11:30am Negative Regulation of caspases
Herman Steller: Rockefeller University, U.S.A
11:30-12:00pm New apoptotic complexes including mitochondrial AK2 and caspase-10 in Cell Death and Tumor
Yong-Keun Jung: Seoul National University, Korea
12:00-12:15pm Calpain Inhibitors Delay Injury-Induced Apoptosis In Adult Mouse Spinal Cord Motor Neurons
Hamid Reza Momeni: University of Arak, Iran
12:15-12:30pm Perturbations In Bioenergetics Of Mitochondria Mediate The Induction Of Apoptosis By Perfluoroalkyl Acids
Konrad Kleszczynski: Medical University of Gdansk, Poland
12:30-2:30pm LUNCH
Chair: Shazib Pervaiz: Singapore
2:30-3:00pm
P63, THE P53 PROGENITOR, BRINGS US FROM CELL DEATH BACK TO STEMNESS
3:00-3:30pm TRPC channels and neuronal survival
Yi-Zheng Wang: Institute of Neuroscience, SIBS, CAS, China
3:30-4:00pm Function And Mechanism Of Stromelysin-3 In Thyroid Hormone Induced Apoptosis During Amphibian Metamorphosis
Yon-Bo Shi: NIH, U.S.A
4:00-4:30pm COFFEE
Session 7: Phagocytosis
Chair: Ray Birge: New Jersey Medical School, U.S.A
4:30-5:00pm Engulfment of apoptotic cells
Shigekazu Nagata: Kyoto University, Japan
5:00-5:30pm Role of TAM (Tyro-3, Axl, Mertk) receptors in immune moduation and phagocytosis of apoptotic cells
Ray Birge: New Jersey Medical School, U.S.A
5:30- 7:30pm Poster Session
7:30pm DINNER
Monday 9th June 2008
Session 8: Targeting Cell Death for Therapeutics
Chair: Boris Zhivotovsky: Karolinska Insitut, Sweden
9:00-9:30am p53 orthologue regulates metabolic enzyme in repairing DNA damage
Mian Wu: Chinese University of Science and Technology, China
9:30-10:00am Modulation of apoptosis-associated gene products by Resveratrol: role in chemo-sensitzation of myeloma and lymphoma tumor cells
Ali Jazirehi: Howard Hughes Medical Insitute, U.S.A
10:00-10:15am Prion Protein and Breast Tumor Resistance to Cell Death
Maryam Mehrpour: CAS, Beijing, China
10:15-10:30am Selective Death Of Tumor Cells By Interference Of The Antisense Non-Coding Mitochondrial Rna (Ncmtrna) With Oligonucleotides
Soledad Viduarre: Chile
10:30-11:00am COFFEE
Chair: Jean-Ehrland Ricci: INSERM, France
11:00-11:30am Mechanisms of cell death/survival in ischemic cardiac diseases
Sergio Lavandero: University of Chile, Chile
11:30-12:00pm Effects of hypoxia on chemotherapeutic drug-induced apoptosis in different cancer cell lines
Carine Michiels: Facultés Universitaires Notre Dame de la Paix, Belgium
12:00-12:30pm Targeting cell death pathways for human diseases
Silvia Soddu: Regina Elena Cancer Insitute, Italy
Session 9: Wrap-up
12:30-1:00pm Perspective of the field and how this meeting fits in it
Guido Kroemer: INSERM, U848, Institut Gustave Roussy, France
1:00-2:00pm LUNCH